2025 Lexus RX 350 Vs. RX 450h+
Lexus RX 350 vs. RX 450h+ at a Glance
- The Lexus RX 350 is the base trim level of the RX lineup, while the RX 450h+ is one of the upper-tier variants.
- In terms of the Lexus RX 350 vs. 450h+ size comparison, you'll see that both models share exterior and interior dimensions.
- The all-gas engine of the RX 350 comes with up to 3,500 pounds of towing capacity when properly equipped, while the 450h+ shouldn't be used for towing.
- However, the electrified power of the 450h+ gives it exceptional fuel economy.
- While the 350 has elevated luxury elements like NuLuxe seating and a 12.3-inch multi-information display, the 450h+ is a step up, including ventilated seats and wireless charging.
What are the differences that you'll find in our Lexus RX 350 vs. RX 450h+ comparison? The Lexus RX 450h+ is the first plug-in hybrid SUV model for the RX lineup, and the RX 350 is the base trim in the series. You get standard luxury features with both Lexus vehicles, but their different powertrains and cabins provide some marked differences.
Once you discover the difference between Lexus RX 350 and 450h+ models, you can decide which one seems right for you. We encourage you to stop by DARCARS Lexus of Silver Spring for a full tour and back-to-back test drives when you're ready.
2025 Lexus RX 350 vs. 2025 RX 450h+ Dimensions
What does the Lexus RX 350 vs. 450h+ size comparison look like when placing these iterations side-by-side? This table compares dimensions, seating, and cargo capacities for the two luxury SUVs. Like you'll see in our Lexus RX 350 vs. Acura MDX guide, both the 350 and 450h+ provide a spacious interior that goes above and beyond the competition.
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| RX 350 FWD | RX 450h+ Luxury AWD | |
|---|---|---|
| Seating | 5 | 5 |
| Cargo Capacity (Min / Max) | 29.6 / 46.2 cu ft | 29.6 / 46.2 cu ft |
| Length | 192.5 in | 192.5 in |
| Width | 75.6 in | 75.6 in |
| Height | 67.3 in | 67.3 in |
| Wheelbase | 112.2 in | 112.2 in |
| Headroom (Front / Rear) |
• 39.5 / 38.6 in (w/o moonroof) • 38.1 / 38.5 in (w/ moonroof) |
37.6 / 37 in |
| Legroom (Front / Rear) | 41.1 / 37.4 in | 41.1 / 37.4 in |
Lexus RX 350 vs. RX 450h+ Specs, Engines & Performance
While the RX 350 vs. RX 450h+ size comparison doesn't reveal many changes, you'll see quite a bit of difference between the Lexus RX 450h+ vs. 350 when comparing performance and engines. The Lexus RX 350 2.4-liter Turbo four-cylinder engine has 275 horsepower that it can deliver, whereas the Lexus RX 450h+ 2.5-liter four-cylinder engine with Lexus Plug-in Hybrid Electric Drive offers 304 horsepower. The RX 350 is a gas-powered vehicle, whereas the RX 450h+ is a plug-in hybrid (PHEV) that can drive on all-electric power for up to 37 miles.1 These metrics are part of the reason you'd pick this SUV over some other members of our inventory, as you can check in our Lexus NX vs. RX comparison.
There are small differences in Lexus RX 350 vs. 450h+ performance features, too, with the RX 350 having the option to reach a 3,500-pound towing capacity when properly equipped. It isn't recommended to tow with the PHEV version, though it compensates with its exclusive EV mode for all-electric driving.
See how the Lexus RX 350 and Lexus RX 450h+ bring various levels of capability to your journey by comparing their horsepower, drivetrains, efficiency, and speed below.
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| RX 350 FWD | RX 450h+ Luxury AWD | |
|---|---|---|
| Engine | 2.4L turbo I-4 | 2.5L plug-in hybrid I-4 |
| Horsepower | 275 | 304 |
| Transmission | 8-speed auto w/ ECT-i | ECVT |
| Drivetrain | FWD, available AWD | AWD |
| EPA-Est. MPG (City / Hwy / Cmb) | 22 / 29 / 25 | – / – / 35 |
| MPGe (Combined) / Electric Range | – / – | 83 MPGe / 37 mi |
| 0–60 MPH Time | 7.6 sec (7.2 sec AWD) | 6.2 sec |
Lexus RX 350 and RX 450h+ Features: Comparing RX Trims
When you review amenities for the new Lexus RX for sale, you will see both shared attributes and key deviations between the 350 and 450h+. They both have the Lexus Safety System+ 3.0 standard that includes Full-Speed Dynamic Radar Cruise Control with Curve Speed Management, a Pre-Collision System with Pedestrian Detection and Intersection Support, Lane Departure Alert with Steering Assist, Road Sign Assist, and Lane Tracing Assist.
Both models also have a Blind Spot Monitor with Rear Cross-Traffic Alert, a Backup Camera, and a 12.3-inch multi-information display – unlike our used Lexus RX 350 variants, which usually have a smaller information screen. Intuitive Parking Assist with Auto Braking is also standard on the RX 350 and RX 450h+.
For technology, similar features include a Lexus 12-speaker Premium Sound System, wireless Android Auto™ and Apple CarPlay®, and Digital Latch with Safe Exit Assist.
So then, what is the difference between Lexus 350 and 450h+ interior comfort and design? The Lexus RX 450h+ is a Luxury grade RX, and so it comes with a standard wireless phone charger, a 14-inch touchscreen, a 10-inch color Head-Up Display, and a 120-volt AC outlet. There are also available upgrades that you can't find on the base RX 350, like optional Advanced Park with Remote Park, Panoramic View Monitor, and a Digital Rearview Mirror. Standard on the RX 350 is a 9.8-inch touchscreen, with the wireless phone charger available as part of the Technology Package. All of these features can be easier to acquire than ever, thanks to our lineup of Lexus RX lease specials.
Comparing Interiors of the RX PHEV vs. RX 350
Interiors of the Lexus RX 350 and Lexus RX 450h+ radiate with luxury, and you will be happy with whichever of these trims that you pick. There are differences in the interior to make note of, like the RX 350 coming with heated front seats and the Lexus RX 450h+ coming with heated and ventilated front seats. The RX 450h+ also has heated and ventilated power-folding/reclining rear outboard seats.
Perforated semi-aniline leather-trimmed upholstery comes on the RX 450h+, whereas NuLuxe material can be found within the RX 350. The RX 350 has eight-way power-adjustable front seats, while the RX 450h+ upgrades to 10-way front-row functionality. As you can see in detail through our Lexus RX 350 interior page, you'll be comfortable and well-cared-for, no matter the edition you choose.
Shop for a Lexus RX 350 or Lexus RX 450h+ at DARCARS Lexus of Silver Spring
Now that you've read the 2025 Lexus RX 350 vs. RX 450h+ guide, does the plug-in hybrid sound like the SUV for you? Are you eager to see the Lexus RX 350? See our inventory for the Lexus RX available in Silver Spring, MD, when you visit us in person. We can guide you throughout the buying or leasing process and help you navigate through RX trim levels to find one at a competitive price. If you prefer an investment with known depreciation, our used Lexus RX models can provide similar technology to the 2025 edition.
We can also give you a tour through all new Lexus models so you can choose the size, comfort, and convenience specifications that match your lifestyle.
Once you find your preferred sedan or SUV, our finance department makes the last steps easy. We'll walk you through the leasing process or the payment plans for your loan so you understand what your budget can get you. Then, we'll see you off in the premium model of your dreams.
Frequently Asked Questions About the Lexus RX 350 vs. RX 450h+
Theoretically, the Lexus RX 450h+ offers a more expansive feature lineup than the baseline RX 350. The Lexus 450h+ is also a plug-in hybrid, meaning that it has significantly better EPA-estimated MPG ratings. However, the Lexus RX 350 is a more accessible model that still offers incredible comfort, like the standard 12.3-inch multi-information display, multi-zone climate control, and ambient illumination.
The Lexus RX 450h+ is estimated to reach 35 MPG (Combined),3 thanks to a 2.5-liter hybrid engine with regenerative braking. However, it is also capable of an all-electric range, with an 83 MPGe4 giving it a maximum of 37 miles of gas-free driving on a full charge. 1 This makes the RX 450h+ one of the longest-range models within the collection.
Lexus RX 350 hybrid configurations, such as the 350h and 350h F SPORT Design, utilize a mild hybrid engine to produce excellent MPG ratings with electrification. The 450h+ is a plug-in hybrid, meaning it has the same functionality as the mild hybrid RX models but can be charged to provide up to 37 miles of all-electric range.1 All will save you plenty of money on fuel overall.
Featured Customer Review
Ariana Armaani,
7/11/2024
We purchased our RX with Alex Rashid and had such a great experience. He and the team made the process very easy. He helped us decide which SUV would meet our family’s needs and budget. Highly recommend!
1EPA-estimated 37 comb all-electric driving range rating on a full charge. For comparison purposes only. Mileage will vary for many reasons, including vehicle's condition and how/where you drive. Battery capacity also decreases with time and use which will reduce range. See www.fueleconomy.gov.
2EPA-estimated 22 city/ 29 hwy/ 25 comb MPG rating for 2025 Lexus RX 350 FWD. Use for comparison purposes only. Your mileage will vary for many reasons, including your vehicle's condition and how/where you drive. See www.fueleconomy.gov.
3EPA-estimated 35 comb MPG rating for 2025 Lexus RX 450h+ Luxury AWD. Use for comparison purposes only. Your mileage will vary for many reasons, including your vehicle's condition and how/where you drive. See www.fueleconomy.gov.
4EPA-estimated 83 MPGe rating for 2025 Lexus RX 450h+ Luxury AWD. MPGe is the EPA equivalent of gasoline fuel efficiency for electric operation. Use for comparison purposes only. Your MPGe/MPG will vary for many reasons, including your vehicle's condition and how/where you drive. See www.fueleconomy.gov.